the effect of 10 weeks of aerobic exercises on glomerular filtration rate (gfr) and urea, creatine and uric acid levels in elderly men with type 2 diabetes

the aim of this study was to determine the effect of aerobic exercises on glomerular filtration rate (gfr) and serum levels of biochemical factors of urea (bun), creatine (cr) and uric acid (uac) in type 2 diabetic men. the sample consisted of 23 type 2 diabetic patients with age range of 45-60 years old who were divided into two groups of experimental (n=13) and control (n=10). experimental group performed aerobic exercises for 10 weeks (2-3 sessions per week, each session 60-90 minutes with intensity of 55-85% of maximum heart rate) whereas control group had their daily activity. blood samples were obtained at baseline and after the intervention phase. the variables were measured using autoanalyzer biochemical sets. to analyze the data, paired sample t test was used. results showed that glomerular filtration rate (gfr) (p=0.028), urea (bun) (p=0.013), and creatine (cr) (p=0.027) reduced in experimental group whereas these variables did not change drastically in control group. these results suggested that 10 weeks of aerobic exercises improve blood urea and creatine while these exercises did not affect blood uric acid (uac). in other words, these exercises can contribute to renal improvement in these patients.